Department of Radiology, Northwestern University, Chicago, Illinois, USA.
J Magn Reson Imaging. 2012 May;35(5):1210-5. doi: 10.1002/jmri.23543. Epub 2012 Jan 26.
To assess the hypothesis that steady-state free procession (SSFP) allows for imaging of the coronary wall under the conditions of fast heart rate in heart transplantation (HTx) patients.
With the approval of our Institutional Review Board, 28 HTx patients were scanned with a 1.5T scanner. Cross-sectional black-blood images of the proximal portions of the left main artery, left anterior descending artery, and right coronary artery were acquired with both a 2D, double inversion recovery (DIR) prepared turbo (fast) spin echo (TSE) sequence and a 2D DIR SSFP sequence. Image quality (scored 0-3), vessel wall area, thickness, signal-to-noise ratio (SNR, vessel wall), and contrast-to-noise ratio (CNR, wall-lumen) were compared between TSE and SSFP.
The overall image quality of SSFP was higher than TSE (1.23 ± 0.95 vs. 0.88 ± 0.69, P < 0.001). SSFP had a higher coronary wall SNR (20.1 ± 8.5 vs. 14.9 ± 4.8, P < 0.001) and wall-lumen CNR (8.2 ± 4.6 vs. 6.8 ± 3.7, P = 0.005) than TSE.
Black-blood SSFP coronary wall MRI provides higher image quality, SNR, and CNR than traditional TSE does in HTx recipients. It has the potential to become an alternative means to noninvasive imaging of cardiac allografts.
评估稳态自由进动（SSFP）在心脏移植（HTx）患者快速心率条件下是否可用于冠状动脉壁成像的假说。
本研究经机构审查委员会批准，对 28 例 HTx 患者进行了 1.5T 扫描仪扫描。使用二维双反转恢复（DIR）准备的涡轮（快速）自旋回波（TSE）序列和二维 DIR SSFP 序列采集左主干、左前降支和右冠状动脉近端的横断面黑血图像。比较 TSE 和 SSFP 之间的图像质量（评分 0-3）、血管壁面积、厚度、信噪比（血管壁 SNR）和对比噪声比（壁腔 SNR）。
SSFP 的总体图像质量优于 TSE（1.23 ± 0.95 比 0.88 ± 0.69，P < 0.001）。SSFP 的冠状动脉壁 SNR（20.1 ± 8.5 比 14.9 ± 4.8，P < 0.001）和壁腔 SNR（8.2 ± 4.6 比 6.8 ± 3.7，P = 0.005）均高于 TSE。
与传统 TSE 相比，黑血 SSFP 冠状动脉壁 MRI 可提供更高的图像质量、SNR 和 CNR。它有可能成为心脏移植物无创成像的替代手段。
