State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
Chem Soc Rev. 2012 Mar 21;41(6):2498-518. doi: 10.1039/c1cs15268h. Epub 2012 Jan 27.
In recent years, Hantzsch esters and their related organic hydride donors have been widely utilized in biomimetic approaches of asymmetric transfer hydrogenation (ATH) reactions. Various compounds containing C=C, C=N and C=O unsaturated functionalities could be reduced in the presence of organocatalysts or transition metal complexes, affording versatile chiral building blocks in high yields and excellent enantioselectivities under mild conditions. In this critical review, recent advances in this area are summarized and classified according to unsaturated functional groups being reduced and catalytic systems employed (91 references).
近年来，Hantzsch 酯及其相关的有机氢化物供体在生物模拟的不对称转移氢化（ATH）反应中得到了广泛的应用。在有机催化剂或过渡金属配合物的存在下，各种含有 C=C、C=N 和 C=O 不饱和官能团的化合物可以被还原，在温和的条件下以高产率和优异的对映选择性得到多功能的手性构建块。在这篇评论中，根据被还原的不饱和官能团和所采用的催化体系对该领域的最新进展进行了总结和分类（91 篇参考文献）。
