Department of Psychology, Psychophysiology Division, Free University, Amsterdam, The Netherlands.
J Psychopharmacol. 1989 Jan;3(3):149-55. doi: 10.1177/026988118900300305.
Sixteen healthy young volunteers (seven females, nine males) received repeated doses of either 30 mg paroxetine, 100 mg maprotiline or placebo in a double-blind crossover study. Each of the three treatments lasted 1 week separated by 2 weeks of no treatment. Treatment order was counterbalanced. Subjects were tested before each treatment period, and after 1 and 7 days of treatment. Measurements were made of mood, perceptual-motor skills, and eye movements including pupil size when subjects were watching a traffic film.
16 名健康的年轻志愿者（7 名女性，9 名男性）在一项双盲交叉研究中接受了重复剂量的帕罗西汀 30 毫克、马普替林 100 毫克或安慰剂治疗。三种治疗方法每种持续 1 周，间隔 2 周不治疗。治疗顺序是平衡的。在每个治疗期之前、治疗后 1 天和 7 天对受试者进行了测试。测量了情绪、知觉运动技能和眼球运动，包括受试者观看交通电影时的瞳孔大小。
