氟马西尼对咪达唑仑的精神运动和遗忘作用的差异影响。
The differential effects of flumazenil on the psychomotor and amnesic actions of midazolam.
机构信息
Departments of Minimally Invasive Surgery, Royal Northern Hospital, Holloway Road, London N7 and Institute of Urology, Shaftesbury Avenue, London WC2.
出版信息
J Psychopharmacol. 1990 Jan;4(1):29-34. doi: 10.1177/026988119000400105.
PMID:22282924
Abstract
Forty-four patients given midazolam prior to day-care urological surgery had the benzodiazepine antagonist, flumazenil, or placebo administered postoperatively. Flumazenil reversed the psychomotor impairments induced by midazolam but not its amnesic effects. There was no evidence of resedation for up to 6 h following the use of flumazenil.
摘要
44 名在日间泌尿科手术前给予咪达唑仑的患者在术后给予苯二氮䓬类拮抗剂氟马西尼或安慰剂。氟马西尼逆转了咪达唑仑引起的精神运动损伤，但没有逆转其遗忘作用。在使用氟马西尼后长达 6 小时内，没有证据表明出现再镇静。
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