Potomac, MD 20854, USA.
J Psychopharmacol. 1990 Jan;4(2):53-62. doi: 10.1177/026988119000400202.
This paper is an edited version of the Max Hamilton Memorial Lecture that was delivered at the annual meeting of the British Association for Psychopharmacology in Cambridge in July 1989. In tribute to Professor Hamilton's pioneering efforts in the field, the lecture focuses on several aspects of the measurement process in psychopharmacology. The role of enumeration in the classification of psychopathology is reviewed and its importance illustrated with an example drawn from the literature. Attention is given to the fundamental link between agreements within the field about the nature and qualities of clinical phenomena and the field's ability to construct and use multi-item rating scales to measure meaningful changes in the intensity of psychopathology. The importance of global assessment as a validation procedure is emphasized and selected hazards to reliable inference are examined.
本文是 1989 年 7 月在剑桥举行的英国精神药理学协会年会上发表的马克斯·汉密尔顿纪念演讲的修订版。为了向汉密尔顿教授在该领域的开拓性努力致敬，演讲重点介绍了精神药理学测量过程的几个方面。本文回顾了列举在精神病理学分类中的作用，并通过文献中的一个例子说明了其重要性。本文还关注了该领域对临床现象的本质和特征的共识，以及该领域构建和使用多项评定量表来衡量精神病理学严重程度的有意义变化的能力之间的基本联系。本文强调了总体评估作为验证程序的重要性，并检查了可靠推论的一些潜在风险。
