[与糖尿病相关的McCune-Albright综合征]

[McCune-Albright syndrome associated with diabetes mellitus].

作者信息

Chihaoui M, Hamza N, Lamine F, Jabeur S, Yazidi M, Ftouhi B, Slimane H

机构信息

Service endocrinologie diabétologie, hôpital La Rabta, Jabbari, 1007 Tunis, Tunisie.

出版信息

Arch Pediatr. 2012 Mar;19(3):282-4. doi: 10.1016/j.arcped.2011.12.018. Epub 2012 Jan 27.

DOI:10.1016/j.arcped.2011.12.018

PMID:22284233

Abstract

McCune-Albright syndrome (MAS) consists of the triad of polyostotic fibrous dysplasia, cutaneous pigmentation, and multiple endocrine abnormalities. Type 1 diabetes mellitus is not included in MAS. We report the case of an 18-year-old girl who presented with McCune-Albright syndrome. The diagnosis was made by the presence of precocious puberty at the age of 6 years, cutaneous pigmentation, polyostotic fibrous dysplasia, and phosphate diabetes. Type 1 diabetes mellitus developed at the age of 16 years. We discuss this case, the relationship between type 1 diabetes mellitus and MAS, with a literature review.

摘要

McCune-Albright综合征（MAS）由多骨型纤维发育不良、皮肤色素沉着和多种内分泌异常三联征组成。1型糖尿病不包括在MAS范围内。我们报告了一名18岁患有McCune-Albright综合征女孩的病例。该诊断基于6岁时出现性早熟、皮肤色素沉着、多骨型纤维发育不良和磷酸盐糖尿病。1型糖尿病于16岁时发病。我们结合文献回顾讨论了该病例以及1型糖尿病与MAS之间的关系。