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老年人不明原因跌倒时神经介导性晕厥的发生率。

The prevalence of Neurally Mediated Syncope in older patients presenting with unexplained falls.

机构信息

Department of General Medicine, Western Hospital, Melbourne, Victoria 3011, Australia.

出版信息

Eur J Intern Med. 2012 Mar;23(2):e48-52. doi: 10.1016/j.ejim.2011.10.010. Epub 2011 Nov 21.

Abstract

AIMS

To determine the prevalence and clinical significance of carotid sinus syndrome (CSS) and vasovagal syncope (VVS), the two common types of Neurally Mediated Syncope (NMS), in a cohort of older patients with unexplained falls.

METHODS

Patients presenting with unexplained and accidental falls were identified from 200 consecutive admissions of falls in patients aged 65 years and older admitted to the Rapid Assessment Medical Unit (RAMU) in a teaching hospital. A sample of unexplained and accidental fallers underwent carotid sinus massage (CSM) and tilt table testing (TTT) as per a standardised protocol. Baseline characteristics, clinical variables and the prevalence of NMS were compared between the two groups.

RESULTS

Falls were unexplained in 26% of patients. The prevalence of NMS was 24% (5/21) among patients with unexplained falls who underwent assessment for NMS, whereas it was nil (0/17) in patients with accidental falls (P=0.050). The prevalence of previous falls was significantly higher in patients with unexplained falls (P=0.0025), but all other baseline characteristics were similar between the two groups.

CONCLUSION

Falls are unexplained in a significant number of older patients presenting to acute hospitals. The assessment of unexplained fallers for NMS is clinically important as this may be aetiologically related in nearly a quarter of these patients.

摘要

目的

确定颈动脉窦综合征(CSS)和血管迷走性晕厥(VVS)这两种常见的神经介导性晕厥(NMS)在一组不明原因跌倒的老年患者中的患病率和临床意义。

方法

从一家教学医院快速评估医疗单位(RAMU)连续收治的 200 例 65 岁及以上跌倒患者中,确定了因不明原因和意外跌倒而就诊的患者。对不明原因和意外跌倒者进行了颈动脉窦按摩(CSM)和倾斜台试验(TTT),采用标准化方案。比较两组间的基线特征、临床变量和 NMS 的患病率。

结果

26%的患者跌倒原因不明。在接受 NMS 评估的不明原因跌倒患者中,NMS 的患病率为 24%(5/21),而意外跌倒患者中则为零(0/17)(P=0.050)。不明原因跌倒患者的既往跌倒发生率明显更高(P=0.0025),但两组间的其他基线特征相似。

结论

在就诊于急性医院的老年患者中,相当一部分跌倒原因不明。对不明原因跌倒患者进行 NMS 评估具有重要的临床意义,因为近四分之一的患者可能与病因相关。

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