Hua X X, Sugaya H, Yoshimura K
Department of Parasitology, Akita University School of Medicine, Japan.
Int J Parasitol. 1990 Aug;20(5):681-3. doi: 10.1016/0020-7519(90)90128-a.
The density of eosinophils in the cerebrospinal fluid (CSF) and blood of male ddY mice infected with Angiostrongylus cantonensis was examined on days 14, 20 and 27 post-infection (p.i.) with discontinuous Percoll gradient centrifugation. Normal blood eosinophils had a density of between 1.070 and 1.080 g ml-1. No significant changes in density in blood eosinophils were noted during the course of the observations. CSF eosinophils began to become hypodense (defined as density less than 1.070 g ml-1) on day 20 p.i., and 88% of eosinophils were hypodense on day 27. Our results suggest therefore that eosinophils probably become hypodense in the CSF and brain tissues, but not in the blood.
在感染广州管圆线虫的雄性ddY小鼠感染后第14、20和27天，采用不连续Percoll梯度离心法检测其脑脊液（CSF）和血液中嗜酸性粒细胞的密度。正常血液嗜酸性粒细胞的密度在1.070至1.080 g/ml之间。在观察过程中，血液嗜酸性粒细胞的密度未发现显著变化。感染后第20天，脑脊液嗜酸性粒细胞开始变为低密度（定义为密度小于1.070 g/ml），在第27天，88%的嗜酸性粒细胞为低密度。因此，我们的结果表明，嗜酸性粒细胞可能在脑脊液和脑组织中变为低密度，但在血液中不会。
