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多西环素与大环内酯类药物联合治疗社区获得性肺炎。

Doxycycline vs. macrolides in combination therapy for treatment of community-acquired pneumonia.

机构信息

Department of Infectious Diseases, Austin Health, Heidelberg, Vic., Australia.

出版信息

Clin Microbiol Infect. 2012 Apr;18(4):E71-3. doi: 10.1111/j.1469-0691.2011.03759.x. Epub 2012 Jan 27.

DOI:10.1111/j.1469-0691.2011.03759.x
PMID:22284533
Abstract

We assessed the comparative efficacy of empirical therapy with beta-lactam plus macrolide vs. beta-lactam plus doxycycline for the treatment of community-acquired pneumonia (CAP) among patients in the Australian Community-Acquired Pneumonia Study. Both regimens demonstrated similar outcomes against CAP due to either 'atypical' (Chlamydophila, Legionella or Mycoplasma spp.) or typical bacterial pathogens.

摘要

我们评估了经验性治疗中使用β-内酰胺类药物加大环内酯类药物与β-内酰胺类药物加多西环素治疗澳大利亚社区获得性肺炎（CAP）患者的疗效。由于“非典型”（衣原体、军团菌或支原体属）或典型细菌病原体引起的 CAP，两种方案的结果均相似。

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