State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, PR China.
Anal Chim Acta. 2012 Feb 24;716:28-33. doi: 10.1016/j.aca.2011.03.012. Epub 2011 Mar 10.
The ionic liquids based simultaneous ultrasonic and microwave assisted extraction (IL-UMAE) technique was first proposed and applied to isolate compounds. The ionic liquids comprising a range of four anions, five 1-alkyl-3-methylimidazolium derivatives were designed and prepared. The results suggested that varying the anion and cation both had apparent effects on the extraction of phenolics. The results also showed that irradiation power, time and solid-liquid ratio significantly affected the yields. The yields of caffeic acid and quercetin obtained by IL-UMAE were higher than those by regular UMAE. Compared with conventional heat-reflux extraction (HRE), the proposed approach exhibited higher efficiency (8-17% enhanced) and shorter extraction time (from 5h to 30s). The results indicated ILUMAE to be a fast and efficient extraction technique. Moreover, the proposed method was validated by the reproducibility and recovery experiments. The ILUMAE method provided good recoveries (from 96.1% to 105.3%) with RSD lower than 5.2%, which indicated that the proposed method was credible. Based on the designable nature of ionic liquids, and the rapid and highly efficient performance of the proposed approach, ILUMAE provided a new alternative for preparation of various useful substances from solid samples.
基于离子液体的超声-微波协同萃取（IL-UMAE）技术首次被提出并应用于化合物的分离。设计并制备了包含四种阴离子和五种 1-烷基-3-甲基咪唑𬭩衍生物的离子液体。结果表明，改变阴离子和阳离子都对酚类化合物的提取有明显的影响。结果还表明，辐照功率、时间和固液比对产率有显著影响。通过 IL-UMAE 得到的咖啡酸和槲皮素的产率高于常规 UMAE。与传统的热回流提取（HRE）相比，该方法具有更高的效率（提高 8-17%）和更短的提取时间（从 5 小时缩短至 30 秒）。结果表明，IL-UMAE 是一种快速有效的提取技术。此外，该方法通过重复性和回收率实验进行了验证。IL-UMAE 方法提供了良好的回收率（96.1%至 105.3%），RSD 低于 5.2%，表明该方法是可靠的。基于离子液体的可设计性和所提出方法的快速高效性能，IL-UMAE 为从固体样品中制备各种有用物质提供了一种新的选择。
