Department of Ophthalmology, Complejo Hospitalario de Navarra, Pamplona, Spain.
Prim Care Diabetes. 2012 Oct;6(3):201-5. doi: 10.1016/j.pcd.2012.01.001. Epub 2012 Jan 28.
To ascertain in real practice the diagnosis rate of diabetic retinopathy (DR) in patients considered to have positive screening test by general practitioners (GPs) and what are the reasons for the false positive diagnosis.
Four GPs previously instructed in the interpretation of retinal photographs evaluated the digital retinography images of patients with diabetes obtained during a 2-year period. When the images were considered normal, a new appointment was scheduled for 1 year later and a report was emailed to the referring physician. Patients with any sign of DR or other suspicious retinal alterations and those whose images were considered difficult or impossible to assess were referred to an ophthalmologist.
A total of 2750 patients were referred for screening. The images of 2036 (74%) patients were considered normal, and the images of 714 (26%) patients were sent to ophthalmologists. Among the referred patients, 392 (55%) did not have DR, 244 (34%) had DR, and 78 (11%) had unreadable images. The retinal images of 240 patients whose fundi were considered normal were read again by ophthalmologists to evaluate false negatives. Of them, 16 patients (7%) had DR but only two patients (1%) had treatable DR.
After adequate training, GPs can screen for DR with a high level of accuracy using non-mydriatic retinography. There is a need to strengthen the training of GPs in order to recognize non-visual threatening abnormalities.
在实际临床实践中确定被全科医生(GP)认为阳性筛查试验的患者中糖尿病视网膜病变(DR)的诊断率,以及假阳性诊断的原因。
4 名先前接受过视网膜照片解读培训的全科医生评估了在 2 年内患有糖尿病的患者的数字视网膜摄影图像。当图像被认为正常时,为患者安排了 1 年后的新预约,并将报告通过电子邮件发送给转诊医生。有任何 DR 迹象或其他可疑视网膜改变的患者,以及那些图像被认为难以或无法评估的患者,将被转诊给眼科医生。
共 2750 名患者被转诊进行筛查。2036 名(74%)患者的图像被认为正常,714 名(26%)患者的图像被发送给眼科医生。在转诊患者中,392 名(55%)没有 DR,244 名(34%)有 DR,78 名(11%)的图像无法读取。眼底被认为正常的 240 名患者的视网膜图像再次由眼科医生阅读,以评估假阴性。其中,16 名患者(7%)患有 DR,但只有 2 名患者(1%)患有可治疗的 DR。
经过充分的培训,GP 使用非散瞳视网膜摄影术可以高度准确地筛查 DR。需要加强对 GP 的培训,以便识别非视觉威胁性异常。