Institute of Technical Chemistry and Environmental Chemistry, Friedrich-Schiller-University Jena, Jena, Germany.
ChemSusChem. 2012 Feb 13;5(2):300-11. doi: 10.1002/cssc.201100445. Epub 2012 Jan 27.
The simple transfer of established chemical production processes from batch to flow chemistry does not automatically result in more sustainable ones. Detailed process understanding and the motivation to scrutinize known process conditions are necessary factors for success. Although the focus is usually "only" on intensifying transport phenomena to operate under intrinsic kinetics, there is also a large intensification potential in chemistry under harsh conditions and in the specific design of flow processes. Such an understanding and proposed processes are required at an early stage of process design because decisions on the best-suited tools and parameters required to convert green engineering concepts into practice-typically with little chance of substantial changes later-are made during this period. Herein, we present a holistic and interdisciplinary process design approach that combines the concept of novel process windows with process modeling, simulation, and simplified cost and lifecycle assessment for the deliberate development of a cost-competitive and environmentally sustainable alternative to an existing production process for epoxidized soybean oil.
简单地将成熟的化学批量生产工艺转移到连续流化学中并不一定会产生更可持续的工艺。详细的工艺理解和审查已知工艺条件的动力是成功的必要因素。虽然重点通常“仅”在于强化传质以在本征动力学下运行，但在恶劣条件下和在连续流工艺的具体设计中也存在很大的强化潜力。在工艺设计的早期阶段需要这种理解和提出的工艺，因为在此期间需要做出关于将绿色工程概念转化为实践所需的最合适工具和参数的决策——通常以后几乎没有进行重大更改的机会。在此，我们提出了一种整体的和跨学科的工艺设计方法，该方法将新工艺窗口的概念与工艺建模、模拟以及简化的成本和生命周期评估相结合，旨在精心开发一种具有成本竞争力和环境可持续性的替代方案，以替代现有的环氧大豆油生产工艺。
