Department of Otolaryngology, Loyola University Medical Center, Maywood, IL, USA.
Int Forum Allergy Rhinol. 2011 Jan-Feb;1(1):38-45. doi: 10.1002/alr.20008. Epub 2011 Feb 8.
Although multiple clinical trials have demonstrated that balloon dilation of sinus ostia in patients diagnosed with chronic rhinosinusitis (CRS) results in sustained symptomatic improvement, less data are available to measure the effects of sinusitis on worker productivity. The objective of our research was to analyze work and activity impairment before and after transantral, endoscopically-guided balloon dilation of the maxillary sinus ostia and ethmoid infundibulum.
Subjects diagnosed with CRS and computed tomography (CT) evidence of disease in the maxillary sinuses alone, or maxillary and anterior ethmoid sinuses, completed the Work Productivity and Activity Impairment (WPAI) questionnaire and the Work Limitation Questionnaire (WLQ) before treatment and at 3, 6, and 12 months postprocedure.
A total of 56 subjects were enrolled and 53 completed the 1-year follow-up. The lost productivity composite score computed from the WLQ improved by 73% (9.0 to 2.4; p < 0.0001) at 1-year follow-up whereas lost productivity at work as measured by the WPAI improved by approximately 76% (38.3 to 9.2; p < 0.0001) 12 months after treatment.
These results indicate that sinus-related health problems impose a substantial burden on work productivity and physical/mental activity levels. Treatment of CRS by dilating the maxillary sinus ostium and ethmoid infundibulum can significantly improve quality of life (QOL) and work productivity.
尽管多项临床试验表明，经鼻窦口球囊扩张术治疗慢性鼻-鼻窦炎（CRS）患者可获得持续的症状改善，但有关窦炎对工作效率影响的资料较少。我们的研究目的是分析经上颌窦口和筛窦漏斗经鼻内镜引导的球囊扩张术前后对工作和活动能力的影响。
诊断为 CRS 且上颌窦存在 CT 证据的患者，或上颌窦和前筛窦均存在 CT 证据的患者，在治疗前、治疗后 3、6 和 12 个月时完成工作效率和活动障碍（WPAI）问卷和工作限制问卷（WLQ）。
共纳入 56 例患者，其中 53 例完成了 1 年随访。WLQ 计算的总生产力丧失综合评分在 1 年随访时改善了 73%（9.0 至 2.4；p<0.0001），而 WPAI 测量的工作生产力丧失在治疗后 12 个月时改善了约 76%（38.3 至 9.2；p<0.0001）。
这些结果表明，与窦相关的健康问题对工作效率和身体/精神活动水平造成了重大负担。通过扩张上颌窦口和筛窦漏斗来治疗 CRS 可以显著提高生活质量（QOL）和工作效率。
