Wilford Hall Medical Center, Department of Otolaryngology-Head and Neck Surgery, Lackland Air Force Base, TX, USA.
Int Forum Allergy Rhinol. 2011 Jan-Feb;1(1):46-9. doi: 10.1002/alr.20002. Epub 2010 Nov 19.
To determine the sinus penetration potential of several commercially available irrigation systems in maximally operated sinus cavities; cadaveric study in a tertiary care center.
Seven fresh cadaver heads with brains removed were maximally dissected to include a Draf III frontal sinusotomy, wide maxillary antrostomy, and complete sphenoethmoidectomy. Drill-holes (4 mm) were created to allow visualization of the irrigations from within the respective sinus cavity. Seven commercially available irrigation systems were then tested according to manufacturer recommendation, and the data recorded using an ordinal scale for comparison.
Among the 3 atomized particle delivery systems tested, the squeeze atomizer took 1.15 attempts, the pump atomizer took 1.85 attempts, and the mechanized atomizer required 30 seconds of continuous application for intrasinus delivery of aerosol (p = 0.009). Penetration with 4 heavy irrigators showed significant variability depending on the sinus cavity being tested. The NeilMed irrigator showed more consistent penetration than any other tested device (p < 0.01). The other systems tested had varying degrees of efficacy, dependent on sinus cavity irrigated.
Delivery of irrigant to maximally operated sinus cavities is variable and highly dependent on the method of nasal delivery. Use of these systems should be tailored appropriately for the desired effect.
为了确定几种市售冲洗系统在最大操作鼻窦腔内的窦穿透潜力；在三级保健中心进行的尸体研究。
将 7 个去除脑组织的新鲜尸体头颅最大程度地解剖，包括 Draf III 额窦切开术、广泛的上颌窦造口术和完全的蝶窦切除术。钻小孔（4 毫米）以允许从各个鼻窦腔内观察冲洗液。然后根据制造商的建议测试了 7 种市售冲洗系统，并使用序数量表记录数据进行比较。
在测试的 3 种雾化颗粒输送系统中，挤压式雾化器需要 1.15 次尝试，泵式雾化器需要 1.85 次尝试，而机械化雾化器需要 30 秒的连续应用才能将气雾剂输送到窦内（p = 0.009）。4 个重型冲洗器的穿透性因测试的鼻窦腔而异。NeilMed 冲洗器的穿透性比任何其他测试设备都更一致（p < 0.01）。其他测试的系统具有不同程度的功效，取决于冲洗的鼻窦腔。
将冲洗液输送到最大操作鼻窦腔内是可变的，并且高度依赖于鼻腔输送的方法。应根据所需效果适当调整这些系统的使用。
