Institute of Bioengineering, Aachen University of Applied Sciences, Jülich, Germany.
J Biomed Mater Res B Appl Biomater. 2012 May;100(4):924-33. doi: 10.1002/jbm.b.32654. Epub 2012 Jan 28.
Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment.
尿道下悬吊带和不同的网片被广泛用于治疗女性压力性尿失禁和脱垂。随着 MiniSlings 的发展和使用较少同种异体材料锚固系统的特殊网片,保持器械在位并施加一些张力(特别是在 MiniSlings 上)变得更加重要。迄今为止,市场上有许多不同公司的不同 MiniSlings 系统,这些系统在使用的网片和锚的结构上有所不同。本文提出了一种新的客观测量方法,用于比较不同 MiniSling 系统(网片和锚)的特性。弹道凝胶可作为软组织替代物。在加载条件下,已经确定了锚的拔出强度或网片收缩等参数的显著差异。锚的形状和尺寸以及网片的结构稳定性对适当的整合至关重要。测试的锚固系统在各自的承载能力下表现出明显不同的机械功能。由于器械在组织中的稳定固定是永久强化的前提,因此所提出的测试系统允许进一步优化锚和网片装置,以提高手术治疗的成功率。