University of Parma, Italy.
Cephalalgia. 2012 Apr;32(5):358-65. doi: 10.1177/0333102411434811. Epub 2012 Jan 27.
In the literature there are few data about the prevalence of primary headaches, including migraine, in the Italian general population. The PACE study (PArma CEfalea, or 'Headache in Parma') is an observational study aimed at detecting the prevalence and clinical features of primary headaches in the city of Parma's adult general population.
A total of 904 subjects representative of Parma's adult general population were interviewed face-to-face by a physician from the Parma Headache Centre. They were given a specially designed and validated questionnaire for the diagnosis of primary headaches according to the ICHD-II criteria.
Past-year adjusted prevalence of definite migraine, including migraine with and without aura and chronic migraine, was 24.7% (95% CI 21.9 to 27.5); 13% (95% CI 9.7 to 16.4) were men and 32.9% (95% CI 28.8 to 37.0) were women. Past-year prevalence of probable migraine was 5.1% (95% CI 3.6 to 6.5): 5.2% (95% CI 3.0 to 7.4) in men and 5% (95% CI 3.1 to 6.9) in women.
The high prevalence of definite migraine is the major difference between our results and the literature data. Such a difference in results may be due to the use of a different investigational approach compared with the other epidemiological studies. However, an actual higher frequency of migraine in the Italian general population cannot be excluded given the lack of studies on this topic.
在文献中，关于意大利普通人群中原发性头痛（包括偏头痛）的患病率数据很少。PACE 研究（帕尔马头痛研究，即“帕尔马头痛”）是一项观察性研究，旨在检测帕尔马市成年普通人群中原发性头痛的患病率和临床特征。
共对 904 名代表帕尔马成年普通人群的受试者进行了面对面访谈，访谈由帕尔马头痛中心的一名医生进行。他们根据 ICHD-II 标准接受了专门设计和验证的原发性头痛诊断问卷。
过去一年确诊偏头痛（包括有和无先兆偏头痛及慢性偏头痛）的调整后患病率为 24.7%（95%CI21.9%至 27.5%）；男性占 13%（95%CI9.7%至 16.4%），女性占 32.9%（95%CI28.8%至 37.0%）。过去一年可能偏头痛的患病率为 5.1%（95%CI3.6%至 6.5%）：男性占 5.2%（95%CI3.0%至 7.4%），女性占 5%（95%CI3.1%至 6.9%）。
我们的研究结果与文献数据的主要区别在于确诊偏头痛的高患病率。这种结果差异可能是由于与其他流行病学研究相比，采用了不同的研究方法。然而，由于缺乏关于这一主题的研究，不能排除意大利普通人群中偏头痛发病率实际更高的可能性。
