Clinical Monitoring Research Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, MD 21702, USA.
J Trop Med. 2012;2012:651927. doi: 10.1155/2012/651927. Epub 2012 Jan 11.
Technology advances in rapid diagnosis and clinical monitoring of human immunodeficiency virus (HIV) infection have been made in recent years, greatly benefiting those at risk of HIV infection, those needing care and treatment, and those on antiretroviral (ART) therapy in sub-Saharan Africa. However, resource-limited, geographically remote, and harsh climate regions lack uniform access to these technologies. HIV rapid diagnostic tests (RDTs) and monitoring tools, such as those for CD4 counts, as well as tests for coinfections, are being developed and have great promise in these settings to aid in patient care. Here we explore the advances in point-of-care (POC) technology in the era where portable devices are bringing the laboratory to the patient. Quality management approaches will be imperative for the successful implementation of POC testing in endemic settings to improve patient care.
近年来，在快速诊断和临床监测人类免疫缺陷病毒（HIV）感染方面的技术取得了进展，这极大地惠及了那些面临 HIV 感染风险、需要护理和治疗的人群，以及撒哈拉以南非洲地区接受抗逆转录病毒（ART）治疗的人群。然而，资源有限、地理位置偏远和气候恶劣的地区无法普遍获得这些技术。正在开发 HIV 快速诊断检测（RDT）和监测工具，例如用于 CD4 计数的工具，以及用于合并感染的检测，这些工具在这些环境中具有很大的应用前景，可以帮助改善患者护理。在这里，我们探讨了在便携式设备将实验室带到患者身边的时代，即时检测（POC）技术的进展。在流行地区，质量管理方法对于成功实施 POC 检测以改善患者护理至关重要。
