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[Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin].

作者信息

Ezhova N M, Garkushina I S, Pisarev O A

出版信息

Prikl Biokhim Mikrobiol. 2011 Nov-Dec;47(6):694-8.

PMID:22288199
Abstract

New hydrophilic polymer sorbents comprising reactionary sites which are complementary to a molecule of antibiotic erythromycin were synthesized by the method of molecular imprinting. A series of similar sorbents without reactionary sites was used for comparison of sorption characteristics. Sorption of erythromycin on both types of polymer sorbents synthesized was studied in a wide range of pH and ionic strength. Selectivity of erythromycin sorption on molecularly imprinted cross-linked polymers was shown to depend on the specific interaction of target molecule with polymer matrix. This type of sorbent is perspective for the development of antibiotic purification directly from a culture medium Saccharopolyspora erythreus.

摘要

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