Department of Epidemiology & Community Medicine, University of Ottawa, Ontario, Canada. sheila.o’
Vox Sang. 2012 Jul;103(1):83-6. doi: 10.1111/j.1423-0410.2012.01584.x. Epub 2012 Jan 31.
Estimates of the viral residual risk should be updated to reflect current incidence of infection in blood donors. Incidence rates were estimated for allogeneic whole-blood donations made to Canadian Blood Services from 2006 to 2009 based on transmissible disease conversions of repeat donations within a 3-year period. Residual risk was estimated as the incidence multiplied by the window period. The residual risk of HIV was 1 per 8 million donations, HCV 1 per 6·7 million donations and HBV 1 per 1·7 million donations. The residual risk remains low and has decreased for HCV since our previous estimates due to reduced incidence.
应对病毒残余风险的估计值进行更新，以反映献血者当前的感染发生率。根据 3 年内重复献血的传染性疾病转化情况，对 2006 年至 2009 年期间加拿大血液服务中心的异体全血捐献进行了发病率估计。残余风险估计值为发病率乘以窗口期。HIV 的残余风险为每 800 万次献血 1 次，HCV 为每 670 万次献血 1 次，HBV 为每 170 万次献血 1 次。由于发病率降低，HCV 的残余风险较之前的估计值有所下降，且仍保持在较低水平。
