Wang Lei, Yu Wenyu, Ren Xiaobai, Lin Jian, Jin Changwen, Xia Bin
Beijing Nuclear Magnetic Resonance Center, Peking University, Beijing 100871, People’s Republic of China.
Biomol NMR Assign. 2012 Oct;6(2):201-3. doi: 10.1007/s12104-012-9357-2.
Human TIG3 protein is a member of H-REV107 protein family which belongs to the type II tumor suppressor family. TIG3 can induce apoptosis in cancer cells, and it also possesses Ca(2+)-independent phospholipase A(1/2) activity. The NMR assignments of the N-terminal domain of TIG3 are essential for its solution structure determination.