Hospital Sant Joan de Déu, Barcelona, Spain.
J Atten Disord. 2013 May;17(4):330-8. doi: 10.1177/1087054711427553. Epub 2012 Jan 30.
To assess the comorbidity of bipolar disorder (BPD) in children with ADHD and to study the psychopathological profile of ADHD children with and without mania.
A total of 100 children with ADHD were assessed with a semistructured diagnostic interview and questionnaires of mania, ADHD, and general psychopathology.
8% of children met criteria for BPD and 6% for BPD-not specified. ADHD children with bipolar spectrum disorder had greater comorbidity with disruptive behavior disorders and scored higher on the Young Mania Rating Scales and on the Child Behavior Checklist (CBCL) Scales of rule-breaking behavior, externalizing problems, and total problems; however, significance on the CBCL Scales was lost when controlling for disruptive behavior disorders.
BPD is frequently associated with ADHD; it has important implications for prognosis and choice of treatment. Differences on the CBCL Scales could be explained by the comorbidity with disruptive behavior disorders rather than by a specific manic profile.
评估注意缺陷多动障碍（ADHD）儿童中双相障碍（BPD）的共病情况，并研究伴或不伴躁狂的 ADHD 儿童的精神病理学特征。
对 100 名 ADHD 儿童进行半结构式诊断访谈和躁狂、ADHD 及一般精神病理学问卷评估。
8%的儿童符合 BPD 标准，6%的儿童符合 BPD 未特指标准。伴双相谱系障碍的 ADHD 儿童与破坏性行为障碍的共病更多，在 Young 躁狂评定量表和儿童行为检查表（CBCL）的破坏性行为、外化问题和总问题量表上的得分更高；然而，当控制破坏性行为障碍时，CBCL 量表的显著性丧失。
BPD 常与 ADHD 相关；这对预后和治疗选择有重要意义。CBCL 量表上的差异可能是由破坏性行为障碍的共病引起的，而不是由特定的躁狂特征引起的。
