Bruker BioSpin AG, Faellanden, Switzerland.
NMR Biomed. 2012 Oct;25(10):1144-51. doi: 10.1002/nbm.2783. Epub 2012 Jan 31.
MRI with zero echo time (ZTE) is achieved by 3D radial centre-out encoding and hard-pulse RF excitation while the projection gradient is already on. Targeting short-T(2) samples, the efficient, robust and silent ZTE approach was implemented for high-bandwidth high-resolution imaging requiring particularly rapid transmit-receive switching and algebraic image reconstruction. The ZTE technique was applied to image extracted human teeth at 11.7T field strength, yielding detailed depictions with very good delineation of the mineralised dentine and enamel layers. ZTE results are compared with UTE (ultra-short echo time) MRI and micro-computed tomography (μCT), revealing significant differences in SNR and CNR yields. Compared to μCT, ZTE MRI appears to be less susceptible to artefacts caused by dental fillings and to offer superior sensitivity for the detection of early demineralisation and caries lesions.
MRI 采用 3D 径向中心外编码和硬脉冲 RF 激发实现零回波时间（ZTE），同时投影梯度已经开启。针对短 T2 样本，实现了高效、稳健且静音的 ZTE 方法，适用于需要特别快速发射-接收切换和代数图像重建的高带宽高分辨率成像。该 ZTE 技术应用于在 11.7T 场强下提取的人牙成像，提供了详细的描绘，对矿化牙本质和牙釉质层具有很好的描绘。将 ZTE 结果与 UTE（超短回波时间）MRI 和微计算机断层扫描（μCT）进行比较，显示 SNR 和 CNR 产生的显著差异。与 μCT 相比，ZTE MRI 似乎对牙填充物引起的伪影不太敏感，并具有更高的早期脱矿和龋齿病变检测灵敏度。
