Xie Yanming, Liu Huan, Wang Yongyan
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2011 Oct;36(20):2855-8.
To study whether there is a causal relationship between the Xiaoke pill and patients' adverse reactions (ADs), and to understand the prevention methods for the ADs.
ADs were evaluated blindly through consulting experts' advice.
81.48% process descriptions on ADs of Xiaoke Pill were clear, 68.52% reports provided enough information on process of ADs, 77.78% of ADs were related with Xiaoke Pill, and 93.33% ADs can be prevented.
Most of ADs are related with Xiaoke pill, and can be prevented through strengthening education on drug use knowledge, strictly indications for taking Xiaoke Pill, adjusting dosage carefully, and controlling drugs combination.
研究消渴丸与患者不良反应之间是否存在因果关系，并了解不良反应的预防方法。
通过咨询专家意见对不良反应进行盲法评估。
消渴丸不良反应过程描述清晰的占81.48%，报告提供不良反应过程足够信息的占68.52%，与消渴丸相关的不良反应占77.78%，93.33%的不良反应可预防。
大多数不良反应与消渴丸有关，可通过加强用药知识教育、严格消渴丸服用指征、谨慎调整剂量以及控制药物联用等方法预防。
