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艰难梭菌:登上大雅之堂的厌氧菌。

Clostridium difficile: the anaerobe that made the grade.

机构信息

UK Anaerobe Reference Laboratory, Microbiology Dept, University Hospital of Wales, Cardiff, UK.

出版信息

Anaerobe. 2012 Apr;18(2):197-9. doi: 10.1016/j.anaerobe.2011.12.021. Epub 2012 Jan 25.

DOI:10.1016/j.anaerobe.2011.12.021
PMID:22293217
Abstract

Unlike other anaerobic bacteria of clinical importance, Clostridium difficile has managed to enter into the realm of public awareness. Following the trail blazed by methicillin-resistant Staphylococcus aureus (MRSA), C. difficile has made the transition from being an obscure anaerobic bacterium, mainly of interest to specialist anaerobic microbiologists, to that of an infamous "superbug" responsible for outbreaks of hospital-acquired infection that commonly result in serious disease and death. This report picks out key moments, particularly in the UK, which tracked the rise in both the public and political awareness of this organism.

摘要

与其他具有临床重要性的厌氧细菌不同,艰难梭菌已经成功进入公众意识领域。艰难梭菌紧随耐甲氧西林金黄色葡萄球菌 (MRSA) 的脚步,已经从一种主要引起专家厌氧微生物学家关注的默默无闻的厌氧细菌,转变为一种臭名昭著的“超级细菌”,它可导致医院获得性感染的爆发,通常会导致严重的疾病和死亡。本报告挑选出了一些关键的时刻,特别是在英国,这些时刻跟踪了公众和政治对这种生物认识的提高。

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Clostridium difficile: the anaerobe that made the grade.艰难梭菌:登上大雅之堂的厌氧菌。
Anaerobe. 2012 Apr;18(2):197-9. doi: 10.1016/j.anaerobe.2011.12.021. Epub 2012 Jan 25.
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Clostridium difficile: from obscurity to superbug.艰难梭菌:从默默无闻至超级细菌
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Engaging patients in the prevention of health care-associated infections: a survey of patients' awareness, knowledge, and perceptions regarding the risks and consequences of infection with methicillin-resistant Staphylococcus aureus and Clostridium difficile.让患者参与预防医源性感染:一项调查患者对耐甲氧西林金黄色葡萄球菌和艰难梭菌感染的风险和后果的认识、知识和看法。
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Sustained reduction in antimicrobial use and decrease in methicillin-resistant Staphylococcus aureus and Clostridium difficile infections following implementation of an electronic medical record at a tertiary-care teaching hospital.在一家三级教学医院实施电子病历后,抗菌药物的使用持续减少,耐甲氧西林金黄色葡萄球菌和艰难梭菌感染减少。
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Collateral damage. The rise of resistant C. difficile.附带损害。耐甲氧西林艰难梭菌的崛起。
Science. 2008 Jul 18;321(5887):360. doi: 10.1126/science.321.5887.360.
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Clostridium difficile infection: a comprehensive review.艰难梭菌感染:全面综述。
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Clostridium difficile infection: an emerging epidemic with more questions than answers.艰难梭菌感染:一个问题多于答案的新兴流行病。
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Epidemic Clostridium difficile.艰难梭菌流行
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Ribotyping in the detection of Clostridium difficile outbreaks in a single university hospital.核糖体分型技术在单所大学医院中艰难梭菌爆发检测中的应用。
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What's lurking under the bed? Persistence and predominance of particular Clostridium difficile strains in a hospital and the potential role of environmental contamination.床下藏着什么?医院中特定艰难梭菌菌株的持续性和优势以及环境污染的潜在作用。
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引用本文的文献

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Emergence and global spread of epidemic healthcare-associated Clostridium difficile.传染病相关艰难梭菌的出现和全球传播。
Nat Genet. 2013 Jan;45(1):109-13. doi: 10.1038/ng.2478. Epub 2012 Dec 9.