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艰难梭菌:从默默无闻至超级细菌

Clostridium difficile: from obscurity to superbug.

作者信息

Brazier J S

机构信息

Anaerobe Reference Laboratory, National Public Health Service for Wales Microbiology, Cardiff, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK.

出版信息

Br J Biomed Sci. 2008;65(1):39-44. doi: 10.1080/09674845.2008.11732796.

DOI:10.1080/09674845.2008.11732796
PMID:18476496
Abstract

According to the UK media and popular press, Clostridium difficile is now a fully fledged member of that notorious but ill-defined group of microorganisms portrayed to the general public as superbugs. Following the trail blazed by methicillin-resistant Staphylococcus aureus (MRSA), C. difficile has made the transition from being an obscure anaerobic bacterium, mainly of interest to specialist anaerobic microbiologists, to that of an infamous superbug responsible for outbreaks of hospital-acquired infection that commonly result in serious disease and death. This review tracks the rise in scientific knowledge and public awareness of this organism.

摘要

据英国媒体和大众报刊报道,艰难梭菌现已成为那群臭名昭著但定义模糊的微生物群体中的正式成员,这些微生物被大众描绘为超级细菌。继耐甲氧西林金黄色葡萄球菌(MRSA)之后,艰难梭菌已从一种主要引起专业厌氧微生物学家关注的 obscure 厌氧菌,转变为一种臭名昭著的超级细菌,它会引发医院获得性感染疫情,通常导致严重疾病和死亡。本综述追踪了关于这种微生物的科学知识增长情况以及公众意识的提高。 (注:obscure 此处暂保留英文,因未准确对应合适中文词汇表达其在文中含义)

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