Lew J F, Wiedermann B L, Sneed J, Campos J, McCullough D
Department of Infectious Diseases, Children's National Medical Center, Washington, D.C. 20010.
J Clin Microbiol. 1990 Sep;28(9):2127-9. doi: 10.1128/jcm.28.9.2127-2129.1990.
A young girl developed an intracranial abscess and necrotizing cellulitis following penetrating injury from a lawn dart. Initial identification of a gram-positive rod growing aerobically from clinical specimens was as a Bacillus organism, but the observation that the isolate grew poorly in subcultures for susceptibility testing but quite well under standard anaerobic culture techniques led to the identification of the organism as an aerotolerant Clostridium tertium. Early management of penetrating head trauma should include cranial imaging studies to detect fractures and intracranial pathology. Clinical microbiologists and clinicians should be aware of the phenomenon of aerotolerance in anaerobic bacteria to avoid errors in choice of antibiotic therapy.
一名年轻女孩在被草地飞镖穿透伤后发生了颅内脓肿和坏死性蜂窝织炎。最初从临床标本中需氧生长的革兰氏阳性杆菌被鉴定为芽孢杆菌属微生物，但观察到该分离株在用于药敏试验的传代培养中生长不佳，而在标准厌氧培养技术下生长良好，这导致该微生物被鉴定为兼性厌氧的第三梭菌。穿透性头部创伤的早期处理应包括进行颅骨影像学检查以检测骨折和颅内病变。临床微生物学家和临床医生应了解厌氧菌的兼性厌氧现象，以避免在选择抗生素治疗时出现错误。
