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[典型形态百分比、顶体异常与多重异常指数之间的关联:潜在的质量指标?]

[Association between the percentages of typical forms, acrosome abnormalities and the multiple anomalies indices: potential quality indicators?].

作者信息

Laudat Antoine, Lecourbe Karine, Joyeux Claudine, Burc-Struxiano Laurence

机构信息

Laboratoire de biologie polyvalente, Unité de biologie de la reproduction et d'assistance médicale à la procréation, Hôpital Louis Pasteur, Le Coudray.

出版信息

Ann Biol Clin (Paris). 2012 Jan-Feb;70(1):105-8. doi: 10.1684/abc.2011.0658.

Abstract

In addition to NF EN ISO 15189, the second version of "GBEA AMP", published in the official journal of the French Republic, had set for "AMP" exams, the actions to be implemented in order to achieve an efficient quality management system. As part of continuous improvement of quality, and besides our external and internal quality systems, we have been developping indicators that will allow an early detection of potential drifts within operators performing sperm morphology testing. We have extracted nearly 1900 sperm morphology tests from our database. These tests were performed by three operators. The analysis of the data collected has shown a cross correlation between the percentages of typical forms, malformative acrosomes and "MAI". We have been using these correlations as quality indicators in our laboratory in order to highlight any potential drift in reading sperm morphology tests.

摘要

除了NF EN ISO 15189之外,在法兰西共和国官方期刊上发表的第二版“GBEA AMP”为“AMP”考试设定了为实现高效质量管理体系而需实施的行动。作为质量持续改进的一部分,除了我们的外部和内部质量体系外,我们一直在开发指标,以便能够早期发现进行精子形态学检测的操作人员中潜在的偏差。我们从数据库中提取了近1900份精子形态学检测报告。这些检测由三名操作人员完成。对收集到的数据进行分析后发现,典型形态百分比、畸形顶体百分比和“MAI”之间存在相互关联。我们一直在实验室中使用这些关联作为质量指标,以突出精子形态学检测读数中任何潜在的偏差。

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