Shaikh H, Khan K S
Department of Pathology, Aga Khan University Medical Centre, Karachi, Pakistan.
J Clin Pathol. 1990 Oct;43(10):817-9. doi: 10.1136/jcp.43.10.817.
As part of a quality assurance programme at the Aga Khan University Medical Centre, Karachi, Pakistan, all hysterectomy specimens were reviewed from January 1986 to December 1989. Adenomyosis was found in 237 of the 419 (56.5%) specimens studied. Of these 237 patients, 232 (97.9%) were parous and 196 (82.8%) were in the fourth and fifth decades of life. This high prevalence in parous women aged 40-59 years was significant. Fibroids, cervicitis, and endometrial hyperplasia were the most common associated diagnoses. Of all the associations studied, only endometrial hyperplasia was significantly more prevalent in the group with adenomyosis. Adenomyosis was stated as an indication for surgery in 69 patients and was confirmed by histopathology in 49 (71%). Preoperative suspicion of adenomyosis was present in 49 (20.6%) patients of all those ultimately found to have the disease. There is a high prevalence of adenomyosis in the population studied, which indicates that the condition may have been underdiagnosed in the past, especially as it is difficult to diagnose without surgery and hysterectomy is currently the only treatment.
作为巴基斯坦卡拉奇阿迦汗大学医学中心质量保证计划的一部分，对1986年1月至1989年12月期间所有子宫切除标本进行了复查。在419份研究标本中，有237份（56.5%）发现了子宫腺肌病。在这237例患者中，232例（97.9%）经产妇，196例（82.8%）年龄在40至59岁之间。40 - 59岁经产妇中这种高患病率具有统计学意义。子宫肌瘤、宫颈炎和子宫内膜增生是最常见的相关诊断。在所有研究的关联中，只有子宫内膜增生在子宫腺肌病组中显著更常见。69例患者将子宫腺肌病作为手术指征，49例（71%）经组织病理学证实。在所有最终被诊断患有该病的患者中，49例（20.6%）术前怀疑患有子宫腺肌病。在所研究的人群中子宫腺肌病患病率很高，这表明该病在过去可能诊断不足，尤其是因为不通过手术很难诊断，而子宫切除术目前是唯一的治疗方法。
