Stoian Cristina A, Lyon Martha, Cox Robin G, Stephure David K, Mah Jean K
Department of Pediatrics;
Paediatr Child Health. 2011 Feb;16(2):82-6. doi: 10.1093/pch/16.2.82.
To examine the relationship between serum vitamin D concentrations, dietary intake and body mass index among healthy children living in Calgary, Alberta.
The present cross-sectional study included healthy children two to 13 years of age who presented to the Alberta Children's Hospital for elective surgery during a 12-month period. Data including the child's weight, height, age, sex, ethnicity, dietary intake, use of vitamin supplements, physical activity and time spent outdoors were collected. Serum concentrations of 25-hydroxyvitamin D (25[OH]D) were measured using commercial immunoradiometric assay kits.
Serum 25(OH)D concentrations were available for 1442 of 1862 participants, of whom 862 (59.8%) were boys. The mean (± SD) serum 25(OH)D concentration was 86.1±35.1 nmol/L (range 10 nmol/L to 323 nmol/L). Five hundred thirty-nine (37.4%) participants had insufficient vitamin D status (25[OH]D between 25 nmol/L and lower than 75 nmol/L), and vitamin D deficiency (25[OH]D 25 nmol/L or lower) was present in 29 subjects (2.0%). Children in the older age group (nine to 13 years) were more likely to have suboptimal vitamin D (P<0.001). Other risk factors significantly associated with suboptimal vitamin D status included overweight or obesity, nonwhite ethnicity, winter months, dietary vitamin D intake of less than 200 IU/day and less time spent outdoors.
A high rate of suboptimal vitamin D concentrations was observed among the participants. Beyond promoting a vitamin D-enriched diet, physicians should also consider the body mass index and other risk factors to determine the optimal vitamin D intake for children living in the area studied.
研究阿尔伯塔省卡尔加里市健康儿童的血清维生素D浓度、饮食摄入与体重指数之间的关系。
本横断面研究纳入了年龄在2至13岁之间、在12个月期间到阿尔伯塔儿童医院接受择期手术的健康儿童。收集了包括儿童体重、身高、年龄、性别、种族、饮食摄入、维生素补充剂使用情况、身体活动及户外活动时间等数据。采用商用免疫放射分析试剂盒测定血清25-羟基维生素D（25[OH]D）浓度。
1862名参与者中有1442人的血清25(OH)D浓度数据可用，其中862人（59.8%）为男孩。血清25(OH)D浓度的均值（±标准差）为86.1±35.1 nmol/L（范围为10 nmol/L至323 nmol/L）。539名（37.4%）参与者维生素D状态不足（25[OH]D在25 nmol/L至低于75 nmol/L之间），29名受试者（2.0%）存在维生素D缺乏（25[OH]D为25 nmol/L或更低）。年龄较大组（9至13岁）的儿童更有可能维生素D水平不理想（P<0.001）。与维生素D水平不理想显著相关的其他风险因素包括超重或肥胖、非白人种族、冬季月份、饮食中维生素D摄入量低于200 IU/天以及户外活动时间较少。
在参与者中观察到较高比例的维生素D浓度不理想情况。除了推广富含维生素D的饮食外，医生还应考虑体重指数和其他风险因素，以确定所研究地区儿童的最佳维生素D摄入量。
