Lee K C, Su W P, Muller S A
Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):1005-8. doi: 10.1016/0190-9622(90)70323-a.
A case of multicentric cloacogenic carcinoma of the perianal skin and vulva in a 79-year-old woman is presented, and the embryologic basis for the multicentricity is discussed. Histologically, cloacogenic carcinoma can be differentiated from other small cell neoplasms that affect the area. Cloacogenic carcinoma should be considered a rare cause of anogenital pruritus. It is important to perform an early biopsy of anogenital lesions that do not respond to conventional therapy.
本文报告了一例79岁女性肛周皮肤和外阴多中心泄殖腔源性癌的病例,并讨论了多中心性的胚胎学基础。从组织学上看,泄殖腔源性癌可与影响该区域的其他小细胞肿瘤相鉴别。泄殖腔源性癌应被视为肛门生殖器瘙痒的罕见原因。对常规治疗无反应的肛门生殖器病变进行早期活检很重要。