García-Muret M P, Pujol R M, Puig L, Moreno A, de Moragas J M
Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):1035-8. doi: 10.1016/0190-9622(90)70332-c.
We report a 42-year-old white bisexual man with disseminated Kaposi's sarcoma limited to the skin and gastrointestinal tract. Results of several serum tests for human immunodeficiency virus (HIV) antibodies have been negative. The CD4/CD8 ratio has remained normal, and his Kaposi's sarcoma has had a benign clinical course during 30 months of follow-up. Similar reports of disseminated Kaposi's sarcoma with a benign clinical course in homosexual or bisexual men without demonstrable HIV infection are reviewed. Some cellular immune impairment that might be more prevalent in the homosexual population may be implicated in the pathogenesis of this type of Kaposi's sarcoma.
我们报告了一名42岁的白人双性恋男性，其患有播散性卡波西肉瘤，病变局限于皮肤和胃肠道。多项人类免疫缺陷病毒（HIV）抗体血清检测结果均为阴性。CD4/CD8比值一直正常，在30个月的随访期间，他的卡波西肉瘤呈良性临床病程。本文回顾了在无明显HIV感染的同性恋或双性恋男性中出现的具有良性临床病程的播散性卡波西肉瘤的类似报告。一些可能在同性恋人群中更普遍的细胞免疫损伤可能与这类卡波西肉瘤的发病机制有关。
