Yang Danna, Wang Lin, Chen Zhiqiang, Li Sai
1 School of Chemical Engineering, Sichuan University, Chengdu 610065, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Dec;28(6):1242-5.
With the emergence of avian flu, influence A virus and other diseases, the development of rapid, real-time, label-free biological sensors has become increasingly significant at the early detection and clinical diagnoses of various diseases. Single-walled carbon nanotubes (SWNTs) have unique one-dimensional structure, special electrical properties, good biocompatibility and size compatibility, so that the SWNTs have great potential uses in the biosensor fields due to these advantages. This article reviews recent examples of carbon nanotubes field-effect transistor (CNTFET) as a label-free biosensors for detecting a variety of biological macromolecules, such as protein, enzyme, DNA, cancer, virus, carbohydrate and so on.
随着禽流感、甲型流感病毒及其他疾病的出现,快速、实时、无标记生物传感器的发展在各种疾病的早期检测和临床诊断中变得越来越重要。单壁碳纳米管(SWNTs)具有独特的一维结构、特殊的电学性质、良好的生物相容性和尺寸兼容性,因此基于这些优势,单壁碳纳米管在生物传感器领域具有巨大的潜在应用价值。本文综述了碳纳米管场效应晶体管(CNTFET)作为无标记生物传感器用于检测多种生物大分子,如蛋白质、酶、DNA、癌细胞、病毒、碳水化合物等的最新实例。