Department of Psychology, University of Bonn, Kaiser-Karl-Ring 9, 53111 Bonn, Germany.
Brain Cogn. 2012 Apr;78(3):268-73. doi: 10.1016/j.bandc.2012.01.003. Epub 2012 Jan 31.
Perspective-taking has become a main focus of studies on moral judgments. Recent fMRI studies have demonstrated that individual differences in brain activation predict moral decision making. In particular, pharmacological studies highlighted the crucial role for the neuropeptide oxytocin in social behavior and emotional perception. In the present study N=154 participants were genotyped for a functional polymorphism (rs2268498) in the promoter region of the OXTR gene. We found a significant difference between carriers and non-carriers of the C-allele in exculpating agents for accidental harms (F((1,152))=11.49, p=.001, η(2)=.07) indicating that carriers of the C-allele rated accidentally committed harm as significantly more blameworthy than non-carriers. This is the first study providing evidence for a genetic contribution to moral judgments.
换位思考已成为道德判断研究的主要焦点。最近的 fMRI 研究表明,大脑激活的个体差异可以预测道德决策。特别是,神经肽催产素在社会行为和情绪感知中的关键作用已得到药理学研究的强调。在本研究中,N=154 名参与者的 OXTR 基因启动子区域的功能性多态性(rs2268498)进行了基因分型。我们发现,在对意外伤害的辩解者中,C 等位基因携带者与非携带者之间存在显著差异(F((1,152))=11.49,p=.001,η(2)=.07),表明 C 等位基因携带者认为意外造成的伤害明显更应受责备。这是第一项提供道德判断存在遗传贡献证据的研究。