Fonseca Lineu C, Tedrus Gloria M A S, Prandi Larissa R, Almeida Adriana M, Furlanetto Danilo S
Faculdade de Medicina, Pontifícia Universidade Católica de Campinas, SP, Brazil.
Arq Neuropsiquiatr. 2011 Dec;69(6):875-81. doi: 10.1590/s0004-282x2011000700005.
To evaluate the relationship between specific cognitive aspects and quantitative EEG measures, in patients with mild or moderate Alzheimer's disease (AD).
Thirty-eight AD patients and 31 controls were assessed by CERAD neuropsychological battery (Consortium to Establish a Registry for AD) and the electroencephalogram (EEG). The absolute power and coherences EEG measures were calculated at rest. The correlations between the cognitive variables and the EEG were evaluated.
In the AD group there were significant correlations between different coherence EEG measures and Mini-Mental State Examination, verbal fluency, modified Boston naming, word list memory with repetition, word list recall and recognition, and constructional praxis (p<0.01). These correlations were all negative for the delta and theta bands and positive for alpha and beta. There were no correlations between cognitive aspects and absolute EEG power.
The coherence EEG measures reflect different forms in the relationship between regions related to various cognitive dysfunctions.
评估轻度或中度阿尔茨海默病（AD）患者特定认知方面与定量脑电图测量之间的关系。
采用CERAD神经心理成套测验（阿尔茨海默病注册协会）和脑电图（EEG）对38例AD患者和31名对照者进行评估。静息状态下计算脑电图测量的绝对功率和相干性。评估认知变量与脑电图之间的相关性。
在AD组中，不同的脑电图相干性测量与简易精神状态检查、言语流畅性、改良波士顿命名、重复单词列表记忆、单词列表回忆和识别以及结构性实践之间存在显著相关性（p<0.01）。这些相关性在δ和θ频段均为负，在α和β频段为正。认知方面与脑电图绝对功率之间无相关性。
脑电图相干性测量反映了与各种认知功能障碍相关区域之间关系的不同形式。
