New York Presbyterian Hospital, NY, 10065, USA.
Asian Pac J Allergy Immunol. 2011 Dec;29(4):297-306.
Allergic rhinitis is a disease with an increasing prevalence throughout the world that severely affects the quality of life of individuals suffering from it. Nasal congestion is the most common and bothersome symptom, and is often associated with sleep-disordered breathing, which is thought to be the reason for sleep impairment in individuals with rhinitis. The end result is a decrease in quality of life and productivity and an increase in daytime sleepiness. Treatment with intranasal corticosteroids has been shown to reduce nasal congestion. Data on sleep-related end points from clinical trials of intranasal corticosteroids indicate that this reduction is associated with improved sleep, reduced daytime fatigue, and improved quality of life. Other therapies, such as montelukast, also have a positive influence on congestion and sleep. This review examines nasal congestion and the associated sleep impairment of allergic rhinitis patients. It explores the adverse effects of disturbed sleep on quality of life and how these conditions can be reduced by therapies that decrease congestion.
变应性鼻炎是一种在全球范围内患病率不断增加的疾病，严重影响患者的生活质量。鼻塞是最常见和最恼人的症状，常与睡眠呼吸紊乱相关，这被认为是鼻炎患者睡眠受损的原因。其结果是生活质量和生产力下降，白天嗜睡增加。鼻内皮质类固醇治疗已被证明可减轻鼻塞。鼻内皮质类固醇临床试验中与睡眠相关的终点数据表明，这种减轻与睡眠改善、白天疲劳减少和生活质量提高有关。其他疗法，如孟鲁司特，也对鼻塞和睡眠有积极影响。这篇综述探讨了变应性鼻炎患者的鼻塞和相关睡眠障碍。它探讨了睡眠紊乱对生活质量的不良影响，以及通过减轻鼻塞的治疗方法如何降低这些情况的发生。
