Lu S N, Chang W Y, Wang L Y, Hsieh M Y, Chuang W L, Chen S C, Su W P, Tai T Y, Wu M M, Chen C J
Department of Medicine, Kaohsiung Medical College, Taiwan, Republic of China.
J Clin Gastroenterol. 1990 Oct;12(5):542-6. doi: 10.1097/00004836-199010000-00011.
A health survey of adults aged 30 years or more was carried out in southwest Taiwan to determine the prevalence of gallstones and to study risk factors associated with gallstones. Blood samples were collected and abdominal sonographic examination and anthropometric measurements were performed on a total of 923 people. The 40 gallstone cases detected resulted in a prevalence of 4.3%. The risk factors explored included age, sex, hepatitis, obesity, hyperlipidemia, and diabetes mellitus (DM). Age and DM were the only significant factors associated with gallstones in our study. With a reference group of 30-39-year-olds as a comparison, multiple logistic regression analysis showed a trend effect with odds ratios of 1.73, 3.74, and 6.32 for age groups of 40-49, 50-59, and 60 or above, respectively. The odds ratio for DM was as high as 2.59. However, sex, body weight index, chronic hepatitis B, and hyperlipidemia were not significantly associated with gallstones.
在台湾西南部对30岁及以上成年人进行了一项健康调查,以确定胆结石的患病率,并研究与胆结石相关的风险因素。共采集了923人的血样,并进行了腹部超声检查和人体测量。检测出40例胆结石病例,患病率为4.3%。所探究的风险因素包括年龄、性别、肝炎、肥胖、高脂血症和糖尿病(DM)。在我们的研究中,年龄和糖尿病是与胆结石相关的仅有的显著因素。以30 - 39岁年龄组作为参照组进行比较,多元逻辑回归分析显示,40 - 49岁、50 - 59岁和60岁及以上年龄组的比值比分别为1.73、3.74和6.32,呈现出一种趋势效应。糖尿病的比值比高达2.59。然而,性别、体重指数、慢性乙型肝炎和高脂血症与胆结石无显著关联。