Laboratory of Exercise Biochemistry and Neuroendocrinology, Institute for Health and Sports Sciences, University of Tsukuba, Tsukuba, Japan.
Neurobiol Aging. 2012 Nov;33(11):2621-32. doi: 10.1016/j.neurobiolaging.2011.12.022. Epub 2012 Feb 1.
A growing number of reports state that regular exercise enhances brain function in older adults. Recently a functional near-infrared spectroscopy (fNIRS) study revealed that an acute bout of moderate exercise enhanced activation of the left dorsolateral prefrontal cortex (L-DLPFC) associated with Stroop interference in young adults. Whether this acute effect is also applicable to older adults was examined. Sixteen older adults performed a color-word matching Stroop task before and after 10 minutes of exercise on a cycle ergometer at a moderate intensity. Cortical hemodynamics of the prefrontal area was monitored with a fNIRS during the Stroop task. We analyzed Stroop interference (incongruent-neutral) as Stroop performance. Though activation for Stroop interference was found in the bilateral prefrontal area before the acute bout of exercise, activation of the right frontopolar area (R-FPA) was enhanced after exercise. In the majority of participants, this coincided with improved performance reflected in Stroop interference results. Thus, an acute bout of moderate exercise improved Stroop performance in older adults, and this was associated with contralateral compensatory activation.
越来越多的报告表明，有规律的运动可以增强老年人的大脑功能。最近一项功能近红外光谱（fNIRS）研究表明，急性适度运动增强了与年轻人 Stroop 干扰相关的左背外侧前额叶皮层（L-DLPFC）的激活。这种急性效应是否也适用于老年人，我们对此进行了研究。16 名老年人在 10 分钟的中等强度自行车测力计运动前后完成了一项颜色-词汇匹配 Stroop 任务。在 Stroop 任务期间，使用 fNIRS 监测前额区域的皮质血液动力学。我们将 Stroop 干扰（不一致-中性）作为 Stroop 表现进行分析。尽管在急性运动前双侧前额区域发现了 Stroop 干扰的激活，但运动后右侧额极区（R-FPA）的激活增强。在大多数参与者中，这与 Stroop 干扰结果反映的表现改善相对应。因此，急性适度运动改善了老年人的 Stroop 表现，这与对侧补偿性激活有关。
