Ranawaka Ranthilaka R, de Silva Nelun, Ragunathan Ramya W
Department of Dermatology, Teaching Hospital Karapitiya, Galle, Sri Lanka.
Dermatol Online J. 2012 Jan 15;18(1):7.
Dermatophytic and non-dermatophytic onychomycosis (NDM) was indistinguishable clinically in our case series. Making a clinical diagnosis of onychomycosis without mycology is the routine practice in Sri Lanka. The prevalence of NDM (45.8%) was very high in our patient population, followed by yeasts (34.1%); dermatophyte infection made up only 20%. Therefore, the treatment of onychomycosis with griseofulvin seems futile. Close contact with soil, the habit of walking barefoot, frequent emersion of hands in water, and a hot, humid climate partly explain the variation in causative pathogens in this case series.
在我们的病例系列中，皮肤癣菌性甲真菌病和非皮肤癣菌性甲真菌病（NDM）在临床上难以区分。在斯里兰卡，不进行真菌学检查就对甲真菌病进行临床诊断是常规做法。在我们的患者群体中，NDM的患病率（45.8%）非常高，其次是酵母菌（34.1%）；皮肤癣菌感染仅占20%。因此，用灰黄霉素治疗甲真菌病似乎是徒劳的。与土壤密切接触、赤脚行走的习惯、手频繁浸水以及炎热潮湿的气候在一定程度上解释了该病例系列中致病病原体的差异。
