Aziz M, Gupta S K, Khan A A
Department of Pathology, JN Medical College and Hospital, Aligarh.
J Indian Med Assoc. 1990 Jun;88(6):160-3.
Serum leucine aminopeptidase (LAP) was estimated in 30 cases of gastro-intestinal cancers, and compared with 50 age and sex matched controls. Highly significant increase of serum LAP was seen in 7 patients with hepatic metastasis (p less than 0.001) from adenocarcinoma of stomach, colon and rectum. The enzyme values showed a highly significant increase in carcinoma of colon, when compared with different anatomical sites of the gastro-intestinal tract (p less than 0.001). However, in adenocarcinoma of stomach and rectum, significantly increased level of serum LAP was observed (p less than 0.01) which contrasted sharply with the normal enzyme values in squamous cell carcinoma of oesophagus and anal canal.
对30例胃肠道癌患者的血清亮氨酸氨基肽酶（LAP）进行了测定，并与50例年龄和性别相匹配的对照组进行了比较。在7例发生肝转移的胃癌、结肠癌和直肠癌腺癌患者中，血清LAP显著升高（p<0.001）。与胃肠道的不同解剖部位相比，结肠癌患者的酶值显著升高（p<0.001）。然而，在胃癌和直肠癌腺癌中，血清LAP水平显著升高（p<0.01），这与食管癌和肛管鳞状细胞癌的正常酶值形成鲜明对比。
