糖皮质激素治疗重症卡氏肺孢子虫肺炎。

Glucocorticoid therapy for severe Pneumocystis carinii pneumonia.

作者信息

Miller R F, Semple S J

机构信息

University College and Middlesex School of Medicine, Middlesex Hospital, London, U.K.

出版信息

J Infect. 1990 Sep;21(2):131-7. doi: 10.1016/0163-4453(90)91571-t.

DOI:10.1016/0163-4453(90)91571-t

PMID:2230171

Abstract

The majority of patients with AIDS and Pneumocystis carinii pneumonia respond to treatment with either high-dose cotrimoxazole or IV pentamidine. Glucocorticoids have been given as 'adjuvant' therapy in those patients who fail to respond to cotrimoxazole or pentamidine. This article discusses the role of glucocorticoids therapy in the treatment of severe Pneumocystis carinii pneumonia and reviews the evidence for their efficacy.

摘要

大多数患有艾滋病和卡氏肺孢子虫肺炎的患者对大剂量复方新诺明或静脉注射喷他脒治疗有反应。对于那些对复方新诺明或喷他脒无反应的患者，已给予糖皮质激素作为“辅助”治疗。本文讨论了糖皮质激素治疗在重症卡氏肺孢子虫肺炎治疗中的作用，并综述了其疗效的证据。