State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
Chem Commun (Camb). 2012 Mar 18;48(23):2861-3. doi: 10.1039/c2cc17861c. Epub 2012 Feb 2.
A novel signal enhanced liquid crystal biosensor based on using AuNPs for highly sensitive DNA detection has been developed. This biosensor not only significantly decreases the detection limit, but also offers a simple detection process and shows a good selectivity to distinguish perfectly matched target DNA from two-base mismatched DNA.
一种新型的基于使用 AuNPs 进行高灵敏度 DNA 检测的信号增强液晶生物传感器已经被开发出来。这种生物传感器不仅显著降低了检测限，而且提供了一个简单的检测过程，并表现出良好的选择性，能够完美地区分完全匹配的靶 DNA 和两个碱基错配的 DNA。
