Nagasawa H
Med Hypotheses. 1979 Apr;5(4):499-510. doi: 10.1016/0306-9877(79)90117-8.
The causes of species differences in mammary tumourigenesis are briefly discussed from the genetical and environmental points of view, although no firm conclusions can be drawn. Distinct differences in mammary gland DNA synthesis were found between female mice and rats, which behave very differently in mammary tumourigenesis. Based on the importance of mammary gland DNA synthesis in mammary tumourigenesis, the differences in mammary gland DNA synthesis between species is hypothesized to be a major cause of the species differences in mammary tumourigenesis.
从遗传学和环境学角度简要讨论了乳腺肿瘤发生中物种差异的原因，尽管无法得出确凿结论。在雌性小鼠和大鼠之间发现了乳腺DNA合成的明显差异，它们在乳腺肿瘤发生方面表现出非常不同的行为。基于乳腺DNA合成在乳腺肿瘤发生中的重要性，推测物种间乳腺DNA合成的差异是乳腺肿瘤发生中物种差异的主要原因。
