Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Oncologist. 2012;17(2):188-91. doi: 10.1634/theoncologist.2011-0332. Epub 2012 Feb 2.
It is widely accepted that traditional models of clinical investigation are becoming unsustainable in oncology and that trials must become more efficient in matching effective treatments to the patients most likely to benefit. In 2008, gastrointestinal oncologists from many countries began a collaboration to improve the design and conduct of clinical trials in their field, through the auspices of a French/U.S. charitable foundation, ARCAD. Whether this model of academic collaboration will be judged a success will depend on the quality of its scientific output during the next few years and whether this output, alongside that of other scientists, groups, and institutions, ultimately leads to more efficient trials and improved treatment options for patients.
人们普遍认为，传统的临床研究模式在肿瘤学领域已经难以为继，临床试验必须提高效率，将有效的治疗方法与最有可能受益的患者相匹配。2008 年，来自许多国家的胃肠肿瘤学家在美国和法国的一家慈善基金会 ARCAD 的支持下开始合作，旨在改进该领域临床试验的设计和实施。这种学术合作模式是否成功，将取决于未来几年的科学产出质量，以及这些产出，以及其他科学家、团体和机构的产出，是否最终能提高临床试验的效率，并为患者提供更多的治疗选择。
