Department of Medicine, Morgantown, West Virginia, USA
West Virginia University Cancer Institute, Morgantown, West Virginia, USA.
Oncologist. 2017 Sep;22(9):1015-1019. doi: 10.1634/theoncologist.2017-0153. Epub 2017 Jun 15.
Historically, advocates of randomized drug treatment trials in oncology contributed to the changing paradigm for testing cancer treatments in the U.S., which led to global efforts to generate evidence of promise in preclinical model systems and translate those findings into improved patient outcomes. In the age of genomic medicine, the challenge to speed the evolution of how clinical trials are conducted in patients with cancer continues.
从历史上看，肿瘤学中随机药物治疗试验的倡导者推动了美国癌症治疗试验范式的改变，这促使全球努力在临床前模型系统中产生有希望的证据，并将这些发现转化为改善患者的治疗结果。在基因组医学时代，加快癌症患者临床试验开展方式演变的挑战仍在继续。
