Bureau of Tobacco Control, New York City Department of Health and Mental Hygiene, 42-09 28th Street, Queens, NY 11101-4132, USA.
Matern Child Health J. 2013 Jan;17(1):49-55. doi: 10.1007/s10995-012-0947-5.
We sought to describe the impact of pica, the craving for and intentional ingestion of substances not defined as food, as a risk factor for lead poisoning in New York City (NYC) pregnant women. In order to describe pregnant women with elevated blood lead levels (BLLs) who report pica, NYC health department data from 491 cases of lead-poisoned pregnant women from January 2001 to June 2009 were reviewed. Descriptive frequencies were obtained for women reporting pica. Data were compared between women reporting and not reporting pica. In NYC, of the 43 (9%) lead-poisoned pregnant women reporting pica, 42 (97.7%) were immigrants and 28 (64.6%) had consumed soil. Compared to lead-poisoned pregnant women not reporting pica, women reporting pica had higher peak BLLs (29.5 vs. 23.8 μg/dL, P = 0.0001), were more likely to have had a BLL ≥ 45 μg/dL (OR = 3.3, 95% CI, 1.25, 8.68) and receive chelation (OR = 10.88, 95% CI, 1.49, 79.25), more likely to have emigrated from Mexico (OR = 3.05, 95% CI, 1.38–6.72), and less likely to have completed high school (OR = indeterminate; 0 vs. 34%; P = 0.003). Among NYC lead-poisoned pregnant women, pica was associated with higher peak BLLs. Providers in NYC, and possibly other urban settings, should be vigilant and question pregnant women, especially immigrants, about pica and strongly consider testing this at-risk population for lead poisoning.
我们旨在描述异食癖(对非食物物质的渴望和有意摄入)作为纽约市(NYC)孕妇铅中毒的风险因素。为了描述报告有异食癖的血铅水平(BLL)升高的孕妇,我们回顾了 2001 年 1 月至 2009 年 6 月期间来自 491 例铅中毒孕妇的数据。对报告有异食癖的女性进行了描述性频率分析。比较了报告和未报告异食癖的女性之间的数据。在 NYC,43 名(9%)报告有异食癖的铅中毒孕妇中,42 名(97.7%)为移民,28 名(64.6%)食用过土壤。与未报告有异食癖的铅中毒孕妇相比,报告有异食癖的孕妇 BLL 峰值更高(29.5 与 23.8μg/dL,P=0.0001),更有可能 BLL≥45μg/dL(OR=3.3,95%CI,1.25,8.68)和接受螯合治疗(OR=10.88,95%CI,1.49,79.25),更有可能从墨西哥移民(OR=3.05,95%CI,1.38–6.72),且更不可能完成高中学业(OR=不确定;0 与 34%;P=0.003)。在 NYC 的铅中毒孕妇中,异食癖与更高的 BLL 峰值相关。NYC 及其他城市地区的医疗保健提供者应保持警惕,询问孕妇,特别是移民,有关异食癖的问题,并强烈考虑对这一高危人群进行铅中毒检测。