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连续妊娠期间的螯合疗法:一则曲折的病例报告。

Chelation during sequential pregnancies: A case report with a twist.

作者信息

Markowitz Morri E, Mercedes Joann, Apt-Dudfield Olga

机构信息

Montefiore Hospital and Medical Center, New York, NY, USA.

出版信息

Obstet Med. 2022 Mar;15(1):54-55. doi: 10.1177/1753495X20975623. Epub 2020 Dec 1.

DOI:10.1177/1753495X20975623
PMID:35444729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9014553/
Abstract

This report summarizes chelation management of lead poisoning occurring during sequential pregnancies. Several aspects make this case unusual; firstly recurrent lead poisoning, secondly treatment with succimer, the use of which is very rarely reported in pregnancy, and thirdly the presence of co-existent vitamin D deficiency and hyperparathyroidism, both potential contributors to bone lead release.

摘要

本报告总结了连续妊娠期间铅中毒的螯合治疗情况。该病例有几个不同寻常的方面;首先是复发性铅中毒,其次是用二巯基丁二酸进行治疗,在孕期使用该药的报道非常罕见,第三是并存维生素D缺乏和甲状旁腺功能亢进,这两者都可能促使骨铅释放。

相似文献

1
Chelation during sequential pregnancies: A case report with a twist.连续妊娠期间的螯合疗法:一则曲折的病例报告。
Obstet Med. 2022 Mar;15(1):54-55. doi: 10.1177/1753495X20975623. Epub 2020 Dec 1.
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The scientific basis for chelation: animal studies and lead chelation.螯合疗法的科学基础:动物研究与铅螯合。
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The treatment of lead poisoning from gunshot wounds with succimer (DMSA).用二巯基丁二酸(DMSA)治疗枪伤所致铅中毒。
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Dimercaptosuccinic acid (succimer; DMSA) in inorganic lead poisoning.二巯基琥珀酸(二巯基丁二酸;DMSA)用于无机铅中毒治疗
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[Effects of chelation therapy with succimer in young rabbits of moderate lead poisoning].[二巯基丁二酸对中度铅中毒幼兔的螯合治疗作用]
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本文引用的文献

1
Blood Lead Levels in U.S. Women of Childbearing Age, 1976-2016.美国育龄妇女血铅水平,1976-2016 年。
Environ Health Perspect. 2020 Jan;128(1):17012. doi: 10.1289/EHP5925. Epub 2020 Jan 16.
2
Examining pica in NYC pregnant women with elevated blood lead levels.检查纽约市血铅水平升高的孕妇异食癖。
Matern Child Health J. 2013 Jan;17(1):49-55. doi: 10.1007/s10995-012-0947-5.
3
Lead exposure in children: prevention, detection, and management.儿童铅暴露:预防、检测与管理。
Pediatrics. 2005 Oct;116(4):1036-46. doi: 10.1542/peds.2005-1947.
4
Severe lead poisoning in pregnancy.妊娠期重度铅中毒
Ambul Pediatr. 2003 Jan-Feb;3(1):37-9. doi: 10.1367/1539-4409(2003)003<0037:slpip>2.0.co;2.
5
Lead poisoning and chelation in a mother-neonate pair.一对母婴的铅中毒与螯合疗法
J Toxicol Clin Toxicol. 2001;39(7):727-31. doi: 10.1081/clt-100108514.