van der Zwet P M, Pinto I M, Serruys P W, Reiber J H
Laboratory for Clinical and Experimental Image Processing, Erasmus University, Rotterdam, The Netherlands.
Int J Card Imaging. 1990;5(2-3):75-83. doi: 10.1007/BF01833976.
For the quantitative analysis of a coronary segment from a coronary (cine)angiogram, an initial path line is required which functions as a model for the subsequent automated contour detection. For on-line applications, a new method for the automated definition of arterial path lines has been developed. Required user-interaction consists of the manual definition of a beginning and an endpoint of the arterial segment to be analyzed. The method is based on a combination of a beam tracer and a box technique. A validation study was performed on 47 non obstructed arteries of various lengths and diameters, and on 56 arterial segments with obstructions (up to 86 percent diameter stenosis). In 89% of the cases an acceptable path line was found after the first iteration; the success score increased to 99%, if a simple manual correction was allowed (2 iterations). The method is extremely fast: the overall average search time for the first iteration was 266 ms, for the second iteration 211 ms. Therefore, it may be concluded that this new technique for the automated definition of arterial path lines is extremely suitable for on-line applications.
为了对冠状动脉（电影）血管造影中的冠状动脉节段进行定量分析，需要一条初始路径线，它作为后续自动轮廓检测的模型。对于在线应用，已经开发出一种自动定义动脉路径线的新方法。所需的用户交互包括手动定义要分析的动脉节段的起点和终点。该方法基于光束跟踪器和盒式技术的组合。对47条不同长度和直径的无阻塞动脉以及56条有阻塞（直径狭窄达86%）的动脉节段进行了验证研究。在89%的病例中，第一次迭代后就找到了可接受的路径线；如果允许进行简单的手动校正（两次迭代），成功得分将提高到99%。该方法速度极快：第一次迭代的总体平均搜索时间为266毫秒，第二次迭代为211毫秒。因此，可以得出结论，这种自动定义动脉路径线的新技术非常适合在线应用。
