• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Purine and pyrimidine nucleotide synthesis and metabolism.嘌呤和嘧啶核苷酸的合成与代谢。
Arabidopsis Book. 2002;1:e0018. doi: 10.1199/tab.0018. Epub 2002 Apr 4.
2
Disorders of purine and pyrimidine metabolism.嘌呤和嘧啶代谢紊乱。
Mol Genet Metab. 2005 Sep-Oct;86(1-2):25-33. doi: 10.1016/j.ymgme.2005.07.027.
3
Purine and pyrimidine nucleotide metabolism in higher plants.高等植物中的嘌呤和嘧啶核苷酸代谢
J Plant Physiol. 2003 Nov;160(11):1271-95. doi: 10.1078/0176-1617-01169.
4
Purine and pyrimidine nucleotide concentrations in cells with decreased hypoxanthine-guanine-phosphoribosyltransferase (HGPRT) activity.次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶（HGPRT）活性降低的细胞中的嘌呤和嘧啶核苷酸浓度。
Adv Exp Med Biol. 1977;76A:326-40. doi: 10.1007/978-1-4613-4223-6_41.
5
Biochemical effect of three different inhibitors of purine/pyrimidine metabolism on differentiation in HL60 cells.三种不同嘌呤/嘧啶代谢抑制剂对HL60细胞分化的生化作用
Leuk Res. 1995 Apr;19(4):263-73. doi: 10.1016/0145-2126(94)00158-7.
6
Purine and pyrimidine metabolism in Leishmania.利什曼原虫中的嘌呤和嘧啶代谢
Adv Exp Med Biol. 2008;625:141-54. doi: 10.1007/978-0-387-77570-8_12.
7
The influence of ammonia on purine and pyrimidine nucleotide biosynthesis in rat liver and brain in vitro.氨对大鼠肝脏和脑体外嘌呤和嘧啶核苷酸生物合成的影响。
Biochem J. 1978 Jun 15;172(3):457-64. doi: 10.1042/bj1720457.
8
Purine Metabolism and Pyrimidine Metabolism Alteration Is a Potential Mechanism of BDE-47-Induced Apoptosis in Marine Rotifer .BDE-47 诱导海洋轮虫凋亡的潜在机制是嘌呤代谢和嘧啶代谢的改变。
Int J Mol Sci. 2023 Aug 12;24(16):12726. doi: 10.3390/ijms241612726.
9
REGULATION AND COORDINATION OF PURINE AND PYRIMIDINE BIOSYNTHESES IN YEAST. I. REGULATION OF PURINE BIOSYNTHESIS AND ITS RELATION TO TRANSIENT CHANGES IN INTRACELLULAR NUCLEOTIDE LEVELS.酵母中嘌呤和嘧啶生物合成的调控与协调。I. 嘌呤生物合成的调控及其与细胞内核苷酸水平瞬时变化的关系。
Biophys J. 1964 May;4(3):151-66. doi: 10.1016/s0006-3495(64)86775-8.
10
Mitochondrial purine and pyrimidine metabolism and beyond.线粒体嘌呤和嘧啶代谢及其他方面。
Nucleosides Nucleotides Nucleic Acids. 2016 Dec;35(10-12):578-594. doi: 10.1080/15257770.2015.1125001.

引用本文的文献

1
Nitrogen Substrate Impacts Microcystis aeruginosa Exometabolome Composition.氮底物影响铜绿微囊藻胞外代谢组组成。
Environ Microbiol Rep. 2025 Oct;17(5):e70189. doi: 10.1111/1758-2229.70189.
2
Association Between Uric Acid to HDL-C Ratio and Liver Transaminase Abnormalities: Insights from a Large-Scale General Population Study.尿酸与高密度脂蛋白胆固醇比值和肝转氨酶异常之间的关联：来自大规模普通人群研究的见解
Medicina (Kaunas). 2025 Aug 5;61(8):1417. doi: 10.3390/medicina61081417.
3
Resistance Response and Regulatory Mechanisms of Ciprofloxacin-Induced Resistant Typhimurium Based on Comprehensive Transcriptomic and Metabolomic Analysis.基于综合转录组学和代谢组学分析的环丙沙星诱导的耐药鼠伤寒沙门氏菌的抗性反应及调控机制
Antibiotics (Basel). 2025 Jul 29;14(8):767. doi: 10.3390/antibiotics14080767.
4
Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth.孕期及早产期间滋养层核苷酸代谢、转运及腺苷信号传导的动态变化。
Sci Rep. 2025 Aug 18;15(1):30275. doi: 10.1038/s41598-025-16183-2.
5
Rationally-Stabilized Inhibited State of IMPDH Proposes a Novel Targeting Approach Involving Its Cross-Domain and Assembly Suppression.肌苷酸脱氢酶的合理稳定抑制状态提出了一种涉及跨结构域和组装抑制的新型靶向方法。
Mol Biotechnol. 2025 Jul 11. doi: 10.1007/s12033-025-01474-w.
6
A novel molecular switch in plant growth: how adenosine kinase activity modulates plant development and growth pathways.植物生长中的一种新型分子开关：腺苷激酶活性如何调节植物发育和生长途径。
J Exp Bot. 2025 Aug 21;76(12):3263-3266. doi: 10.1093/jxb/eraf232.
7
A mechanism of global gene expression regulation is disrupted by multiple disease states and drug treatments.一种全球基因表达调控机制被多种疾病状态和药物治疗所破坏。
PLoS One. 2025 May 8;20(5):e0317071. doi: 10.1371/journal.pone.0317071. eCollection 2025.
8
Size-Dependent Cytotoxicity and Multi-Omic Changes Induced by Amorphous Silicon Nanoparticles in HepG2 Cells.非晶硅纳米颗粒对HepG2细胞诱导的尺寸依赖性细胞毒性和多组学变化
Toxics. 2025 Mar 21;13(4):232. doi: 10.3390/toxics13040232.
9
Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling in the ES-2 Ovarian Carcinoma Cell Line, Influencing Cell Proliferation, Quiescence, and Chemoresistance in a Cell-of-Origin-Specific Manner.游离DNA（cfDNA）调节ES-2卵巢癌细胞系中的代谢重塑，以细胞起源特异性方式影响细胞增殖、静止和化疗耐药性。
Metabolites. 2025 Apr 2;15(4):244. doi: 10.3390/metabo15040244.
10
Cell-Free DNA (cfDNA) Regulates Metabolic Remodeling, Sustaining Proliferation, Quiescence, and Migration in MDA-MB-231, a Triple-Negative Breast Carcinoma (TNBC) Cell Line.游离DNA（cfDNA）调节三阴性乳腺癌（TNBC）细胞系MDA-MB-231中的代谢重塑、维持增殖、静止和迁移。
Metabolites. 2025 Mar 27;15(4):227. doi: 10.3390/metabo15040227.

本文引用的文献

1
Effect of allopurinol on the utilization of purine degradation pathway intermediates by tobacco cell cultures.别嘌醇对烟草细胞培养物嘌呤降解途径中间产物利用的影响。
Plant Cell Rep. 1985 Dec;4(6):304-6. doi: 10.1007/BF00269884.
2
Evidence that a Single Polypeptide Catalyses the Two Step Conversion of Orotate to UMP in Cells from a Tomato Suspension Culture.证据表明，在番茄悬浮培养细胞中，一种单一多肽催化乳清酸到 UMP 的两步转化。
J Plant Physiol. 1984;116(4):301-11. doi: 10.1016/S0176-1617(84)80109-1. Epub 2012 Jan 20.
3
Isolation and Characterization of UMP Synthase Mutants from Haploid Cell Suspensions of Nicotiana tabacum.从烟草的单倍体细胞悬浮液中分离和表征 UMP 合酶突变体。
Plant Physiol. 1992 Jul;99(3):1216-25. doi: 10.1104/pp.99.3.1216.
4
Metabolism of Benzyladenine is Impaired in a Mutant of Arabidopsis thaliana Lacking Adenine Phosphoribosyltransferase Activity.在缺乏腺嘌呤磷酸核糖转移酶活性的拟南芥突变体中，苄基腺嘌呤的代谢受到损害。
Plant Physiol. 1991 Mar;95(3):900-8. doi: 10.1104/pp.95.3.900.
5
Positive selection for male-sterile mutants of Arabidopsis lacking adenine phosphoribosyl transferase activity.拟南芥腺嘌呤磷酸核糖基转移酶活性缺失雄性不育突变体的正向选择。
Plant Physiol. 1988 Apr;86(4):1150-4. doi: 10.1104/pp.86.4.1150.
6
Localization of carbamoylphosphate synthetase and aspartate carbamoyltransferase in chloroplasts.氨甲酰磷酸合成酶和天冬氨酸氨甲酰基转移酶在叶绿体中的定位。
Plant Physiol. 1986 Jan;80(1):126-9. doi: 10.1104/pp.80.1.126.
7
Purine catabolism in plants : purification and some properties of inosine nucleosidase from yellow lupin (lupinus luteus L.) seeds.植物中的嘌呤分解代谢：从黄羽扇豆（羽扇豆）种子中纯化和研究肌苷核苷酶的一些性质。
Plant Physiol. 1982 Aug;70(2):344-9. doi: 10.1104/pp.70.2.344.
8
Effects of Allopurinol [4-Hydroxypyrazolo(3,4-d)Pyrimidine] on the Metabolism of Allantoin in Soybean Plants.别嘌呤醇[4-羟基吡唑并(3,4-d)嘧啶]对大豆植株中尿囊素代谢的影响。
Plant Physiol. 1978 Jul;62(1):134-8. doi: 10.1104/pp.62.1.134.
9
Properties of pea seedling uracil phosphoribosyltransferase and its distribution in other plants.豌豆幼苗尿嘧啶磷酸核糖基转移酶的性质及其在其他植物中的分布。
Plant Physiol. 1978 Mar;61(3):442-6. doi: 10.1104/pp.61.3.442.
10
Cytochemical Analysis of Pollen Development in Wild-Type Arabidopsis and a Male-Sterile Mutant.野生型拟南芥和雄性不育突变体花粉发育的细胞化学分析
Plant Cell. 1990 Sep;2(9):877-889. doi: 10.1105/tpc.2.9.877.

Purine and pyrimidine nucleotide synthesis and metabolism.

作者信息

Moffatt Barbara A, Ashihara Hiroshi

出版信息

Arabidopsis Book. 2002;1:e0018. doi: 10.1199/tab.0018. Epub 2002 Apr 4.

DOI:10.1199/tab.0018
PMID:22303196
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3243375/
Abstract
摘要