Oliviero F, Scanu A, Punzi L
Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Padova, Padova, Italy.
Reumatismo. 2012 Jan 19;63(4):221-9. doi: 10.4081/reumatismo.2011.221.
Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.
尿酸钠（MSU）、二水焦磷酸钙（CPPD）和碱性磷酸钙（BCP）晶体沉积在关节及周围组织中，会引发急性炎症和慢性软骨损伤。许多内源性物质和物理化学条件会影响它们的沉淀、生长甚至溶解，从而调节它们的代谢和炎症活性。我们综述了MSU和钙晶体在关节内如何形成以及调节它们形成的各种因素。
