Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Hospital, Baltimore, MD, USA.
J Neuroimaging. 2012 Apr;22(2):e18-41. doi: 10.1111/j.1552-6569.2011.00690.x. Epub 2012 Feb 3.
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in children. The unique biomechanical, hemodynamical, and functional characteristics of the developing brain and the age-dependent variance in trauma mechanisms result in a wide range of age specific traumas and patterns of brain injuries. Detailed knowledge of the main primary and secondary pediatric injuries, which enhance sensitivity and specificity of diagnosis, will guide therapy and may give important information about the prognosis. In recent years, anatomical but also functional imaging methods have revolutionized neuroimaging of pediatric TBI. The purpose of this article is (1) to comprehensively review frequent primary and secondary brain injuries and (2) to give a short overview of two special types of pediatric TBI: birth related and nonaccidental injuries.
创伤性脑损伤(TBI)是儿童发病率和死亡率的主要原因。发育中大脑的独特生物力学、血液动力学和功能特征以及创伤机制的年龄依赖性差异导致了广泛的特定年龄的创伤和脑损伤模式。对主要原发性和继发性儿科损伤的详细了解可提高诊断的敏感性和特异性,并指导治疗,还可能提供有关预后的重要信息。近年来,解剖学甚至功能成像方法彻底改变了儿科 TBI 的神经影像学。本文的目的是(1)全面回顾常见的原发性和继发性脑损伤,(2)简要介绍两种特殊类型的儿科 TBI:与出生相关的和非意外伤害。